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Article
Publication date: 1 February 1993

Judith A. Carter

Consider the prospects for keyword searching with the advent ofuser‐access to PRISM interlibrary lending system in December 1992.Offers some helpful avice for starting out with…

Abstract

Consider the prospects for keyword searching with the advent of user‐access to PRISM interlibrary lending system in December 1992. Offers some helpful avice for starting out with PRISM. Considers restrictions to using keyword searching for CAT ME Plus and CAT CD450 users. Outlines keyword commands, keyword searches, character masking, HRR prompt and revise features, error messages and Help as well as Internet access.

Details

OCLC Systems & Services: International digital library perspectives, vol. 9 no. 2
Type: Research Article
ISSN: 1065-075X

Keywords

Article
Publication date: 1 February 1974

Roberta A. Scull

This annotated listing of 131 United States Government bibliographies with 1973 imprints partially represents the broad scope of Federal interest. THE MONTHLY CATALOG OF U.S…

Abstract

This annotated listing of 131 United States Government bibliographies with 1973 imprints partially represents the broad scope of Federal interest. THE MONTHLY CATALOG OF U.S. GOVERNMENT PUBLICATIONS was the primary index searched in locating these documents, though other conventional and unconventional methods were used. Since the search cut‐off date was the February 1974 MONTHLY CATALOG, a number of 1973 bibliographies may not be listed here. However, it is the compiler's objective to include all 1973 bibliographies in a forthcoming Pierian Press publication, BIBLIOGRAPHY OF UNITED STATES GOVERNMENT BIBLIOGRAPHIES 1968–1973.

Details

Reference Services Review, vol. 2 no. 2
Type: Research Article
ISSN: 0090-7324

Article
Publication date: 2 October 2019

Huailing Wang, Jie Liu, Xiaoyu Liu and Zhigang Liu

Blueberry contains bioactive compounds which are beneficial to organisms, such as phenolics and flavonoids. The purpose of this paper is to evaluate the potential protective…

Abstract

Purpose

Blueberry contains bioactive compounds which are beneficial to organisms, such as phenolics and flavonoids. The purpose of this paper is to evaluate the potential protective effects of blueberry extracts (BE) on H2O2-induced HepG2 cells.

Design/methodology/approach

Cell protection was evaluated via the survivals of the cell. Reactive oxygen species (ROS) level, antioxidant enzyme and malondialdehyde (MDA) were detected. Western blot was carried out to analysis protein which was related to the cell apoptosis pathway. Changes in morphology including: cell total apoptosis/necrosis and G0/G1 cycle arresting were also concomitant.

Findings

The levels of ROS and malondialdehyde (MDA) reduced after the BE treatment while the contents of superoxide dismutase, and glutathione peroxidase (GSH-Px) increased in HepG2 cells induced by H2O2. Furthermore, mechanistic studies indicated that BE regulated the activation of mitochondrial apoptosis signal-regulating (Bcl-2, Bax). Qu was used as a positive control group. All these results demonstrated that the BE have a potential against oxidative stress in vitro.

Originality/value

Few studies have focused on the bioactivities of blueberry on oxidative stress. Taken together, the results confirm that polyphenol-enriched BE have the ability to protect against oxidative stress in cells. It has a great potential as a functional food ingredient to health benefits. Furthermore, this work showed the value of using simple biological models to screen for compounds that are of interest for food and pharmacological industry.

Details

British Food Journal, vol. 121 no. 11
Type: Research Article
ISSN: 0007-070X

Keywords

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